Abstract
Introduction: Hepatitis B virus infection is a major health problem, and since there is no complete treatment for it, the prevention is a significant factor in order to control the infection. Evaluation of the vaccination titer of clinical students and assessment of its relationship with possible effective factors provide valuable information about the time of titer evaluation and the function of the vaccine and also identify the necessity of the booster dose. Material and Methods: In this cross-sectional, Descriptive-analytical, observational study, antibody titers of 64 clinical students of Semnan University of Medical Sciences were evaluated. After completing the consent form, the anti-HBS test was prescribed for all students participating in the study. Results: The titers of 49 students (76.6%) were above 100 and 15 of them (23.4%) had titers between 10-100. There was significant relationship between antibody titer and age, but no significant relationships were found between antibody titer and variables such as sex, BMI, smoking, and the time passed from the last dose of vaccination. Conclusion: Based on the findings, the antibody titer and immunogenicity decrease with aging. This specifies the necessity of evaluation of the antibody titer in vaccinated dental students who are in the high-risk group.